Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

Gulhane School of Medicine78 enrolled

Overview

In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Polycystic Ovary Syndrome

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Absence of significant abnormalities on physical examination except hirsutism * no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy * normal thyroid function and prolactin level * absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease Exclusion Criteria: * Pregnant * ovarian tumors * congenital adrenal hyperplasia or BMI greater than 30 kg/m2

Locations (1)

Gulhane School of Medicine Etlik

Ankara, Turkey (Türkiye)

Data from ClinicalTrials.gov

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