Identification of Potential Biomarkers of Peptide Immunotherapy. Part 1 - Proteomics Analysis

Inclusion Criteria: * Male or Female, aged 18-65 years * A minimum 1-year documented history of rhinoconjunctivitis on exposure to cats. * Positive skin prick test to cat allergen with a wheal diameter at least 3mm larger than that produced by the negative control. * Regular exposure to a cat in their normal living or working circumstances throughout the course of the study. * Minimum qualifying rhinoconjunctivitis symptom scores Exclusion Criteria: * History of asthma * A history of anaphylaxis to cat allergen * A history of allergen immunotherapy in the previous 10 years, or in the previous 3 years for pre-seasonal immunotherapy treatments * A history of any significant disease or disorder (e.g. autoimmune, cardiovascular, pulmonary, gastrointestinal, liver, renal, neurological, musculoskeletal, endocrine, metabolic, neoplastic/malignant, psychiatric, major physical impairment, severe atopic dermatitis)