Resection for Multiple Hepatocellular Carcinomas (HCC)

University of Milan87 enrolled

Overview

Surgical resection in patients with multiple hepatocellular carcinomas (HCC) remains controversial. The aim of this study was to investigate the outcome of a consecutive cohort of patients resected for multiple HCC, without macrovascular invasion, in order to identify clinically reliable parameters to select patients for surgery.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hepatocellular Carcinoma Multiple Tumors Cirrhosis

Interventions

hepatic resectionPROCEDURE

surgical resection of the liver for multiple HCC

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * patients with multiple HCC without macrovascular invasion on liver cirrhosis Exclusion Criteria: * macrovascular invasion; * normal liver; * distant or lymphnodes metastasis

Locations (1)

University of Milan IRCCS Istituto Clinico Humanitas

Rozzano, Milan, MI, Italy

Outcomes

Primary Outcomes

Overall survival plus multivariate analysis

The primary endpoint of the study was the overall survival of patients resected for multiple HCC, and the univariate and multivariate analyses of prognostic factors for overall survival.

Time frame: 10 years

Secondary Outcomes

Disease-free survival

The secondary endpoint was the disease-free survival.

Time frame: 10 years

Data from ClinicalTrials.gov

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