Efficacy Study of Minoxidil Lotion Versus Combined Minoxidil and Finasteride Lotion to Treat Male Pattern Hair Loss

Mae Fah Luang University Hospital40 enrolled

Overview

The purpose of this study is to compare the efficacy of 3% Minoxidil lotion and 3% Minoxidil with 0.1% Finasteride lotion for 6 months in male pattern hair loss.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Androgenetic Alopecia

Interventions

3%Minoxidil lotionDRUG

3% Minoxidil lotion apply two times a day

3% Minoxidil with 0.1% Finasteride lotionDRUG

3% Minoxidil with 0.1% Finasteride lotion apply two times a day.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * male, age 18-15 years * androgenetic alopecia grade 3V to 5 ( Norwood-Hamilton classification) Exclusion Criteria: * use minoxidil in 6 months * use finasteride in 12 months * use ketoconazole, tar, selenium shampoo, topical tretinoin, topical steroid in 2 weeks * seborrheic dermatitis or psoriasis on scalp * history of allergy to minoxidil, finasteride

Locations (1)

Mae Fah Luang University Hospital(Bangkok)

Bangkok, Bangkok, Thailand

Outcomes

Primary Outcomes

The mean change of hair count from baseline and 6 months

Total hair count on the vertex is measured on 1 cm2 circular area. The mean change in hair count is compared at baseline and 6 months.The significance of change is determined by Unpaired t Test.

Time frame: baseline and 6 months

Secondary Outcomes

Global photographic assessment by dermatologists

Photographs of the vertex scalp are taken at baseline and 6 months. A panel of 3 dermatologists assesssed the change in hair growth using a 7-point scale.

Time frame: baseline and 6 months

Data from ClinicalTrials.gov

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