Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease

Final diagnostic criteria: * Crohn' disease (at least two of the following is met) 1. Clinical history of abdominal pain, weight loss, malaise, diarrhea, and/or rectal bleeding 2. Endoscopic findings of mucosal cobblestoning, linear ulceration, skip areas, or perianal disease 3. Radiologic findings of stricture, fistula, mucosal cobblestoning, or ulceration 4. Macroscopic appearance of bowel-wall induration, mesenteric lymphadenopathy, and "creeping fat" at laparotomy 5. Pathologic findings of transmural inflammation and/or epithelioid granulomas * Intestinal tuberculosis(at least one of the following is met) 1. Histologic evidence of caseating granulomas 2. Histologic demonstration of acid-fast bacilli 3. Growth of M. tuberculosis on tissue culture 4. Clinical, colonoscopic, radiologic, and/or operative evidence of Intestinal tuberculosis with proved tuberculosis elsewhere 5. Response to antituberculous therapy without subsequent recurrence in patients with clinical, colonoscopic, radiologic, and/or operative evidence of Intestinal tuberculosis Exclusion Criteria: * Refusal to participate in the study * Age: 15 years or younger * Comorbidity with acute infectious disease * Pregnancy * Previous history of medication including anti-TB drugs, immunosuppressive drugs, and chemotherapeutic agents\\ * Use of antibiotics within the previous three months