This study was an extension to study CQTI571A2102 and was to evaluate the long-term safety, tolerability and efficacy of QTI571 (imatinib) in severe pulmonary arterial hypertension patients.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
17
200 mg or 400 mg qd
Novartis Investigative Site
Mineola, New York, United States
Novartis Investigative Site
Darlinghurst, New South Wales, Australia
Novartis Investigative Site
Leuven, Belgium
Novartis Investigative Site
Hanover, Germany
Number of Patients With Adverse Events, Serious Adverse Events and Deaths
Adverse event monitoring was conducted throughout the trial.
Time frame: 144 weeks
Change From Baseline in the Six Minute Walk Distance (6MWD)
Time frame: baseline, 144 weeks
Time to Clinical Worsening (TTCW) Endpoints
Time frame: 144 weeks
Medical Resource Utilization
Time frame: 144 weeks
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Novartis Investigative Site
Roma, RM, Italy
Novartis Investigative Site
Vilnius, Lithuania
Novartis Investigative Site
London, United Kingdom