Effects of Telmisartan/Hydrochlorothiazide Treatment in Hypertensive Patients Under Real-life Setting

Bayer1,586 enrolled

Overview

One of the most common adverse effects resulting from the therapy with thiazides, thiazide-like diuretics and loop diuretics is increased potassium secretion. Disregulation of plasma potassium may be a life-threatening condition due to increased risk of arrythmias. Moreover, it has been postulated that decrease in plasma potassium level may negatively affect glucose metabolism resulting in the increased risk of new-onset type 2 diabetes.The main goal of this study is to assess the efficacy and safety of telmisartan/hydrochlorothiazide in a broad population of hypertensive patients, including the effects of the therapy on plasma potassium level and also on selected parameters of glucose and lipid metabolism.

Study Type

OBSERVATIONAL

Enrollment

1,586

Conditions

Primary Hypertension

Interventions

Telmisartan/hydrochlorothiazide (Pritor Plus, BAY98-7103)DRUG

Patients treated with telmisartan/hydrochlorothiazide tablets under the real-life setting. Dosing regimen customised to the needs of each participating patient according to the investigators assessment

Outcomes

Primary Outcomes

Change in systolic (SBP) and diastolic (DBP) blood pressure between first and final visit

Time frame: approx. 3 mths after telmisartan/hydrochlorothiazide treatment initiation