Cognitive Training in Parkinson's Disease

University Hospital, Basel, Switzerland39 enrolled

Overview

The study evaluates a computerized cognitive therapy in patients with Parkinson's disease who have a mild cognitive impairment or mild dementia. The control group is "trained" using Nintendo Wii. The main outcome parameter is a neuropsychological evaluation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Mental Competence

Interventions

Cognitive TrainingOTHER

computer gameOTHER

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Parkinson's disease and mild cognitive impairment (MCI) or mild dementia Exclusion Criteria: * Moderate or severe dementia, other pathologies of the brain, physical conditions that prevent the participation, unsufficient knowledge of german, pregnancy

Locations (1)

University Hospital Basel

Basel, Switzerland

Outcomes

Primary Outcomes

Neuropsychological parameters: Tests of episodic memory, working memory, executive functions, visio-construction

Neuropsychological tests: mini mental status (MMS), Clock drawing test, Boston Naming Test, Calculating, Semantic Fluency, Phonematic Fluency, California Verbal Learning Test, Corsi Block Tapping Test, Trail Making Test, Digit Span, Testbatterie zur Aufmerksamkeitsprüfung (alteredness, Working Memory, Divided Attention, Flexibility), Wisconsin Card Sorting Test, Apraxias, 5 Points Test, Mosaik Test

Time frame: Neuropsychological assessment immediatly before and after the training and 6 month later

Data from ClinicalTrials.gov

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