Safety, Tolerability, and Pharmacokinetics of AMG 827 in Adolescents With Asthma

Inclusion Criteria: * Male and/or female subjects 12 to \< 18 years of age at the time of randomization * Male and/or female subjects between 18 and 50 years of age (inclusive) at the time of randomization * Body weight ≥ 36 kg at screening * Intermittent or mild to moderate persistent asthma for at least the past 3 months prior to study enrollment (as defined by the 2004 Global Initiative for Asthma \[GINA\] guidelines. Exclusion Criteria: * Experienced an asthma exacerbation (defined as a disease episode resulting in treatment in an emergency room or urgent care facility, or an episode treated with oral corticosteroids) during the 3 months prior to study enrollment. * Hospitalized for asthma during the 6 months prior to study enrollment; or ever intubated for the treatment of asthma. * Use of oral corticosteroids within 3 months prior to study enrollment.