Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E.

KU Leuven1,500 enrolled

Overview

Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Acutely Ill Children in a High Prevalent Setting: The Paediatric Accidents \& Emergencies through prospective observational data collection concerning specific items from the clinical and technical examination in diagnosing serious infections, such as meningitis, sepsis, pneumonia, pyelonephritis, bronchiolitis with hypoxia. Eventually we will attempt to validate a vital signs and symptoms rule derived from multiple low to high prevalent settings of acutely ill children.

Study Type

OBSERVATIONAL

Enrollment

1,500

Conditions

Community-Acquired Infections Respiratory Tract Infections Sepsis Urinary Tract Infections Meningitis Gastroenteritis

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Children aged 1 month to 16 years * Acute illness episode of maximum 5 days Exclusion Criteria: * recent trauma * neurological conditions * intoxication * psychiatric of behavioural disorders without a somatic cause * acute exacerbation of a chronic condition (asthma, known immunodeficiency, diabetes, cystic fibrosis, etc)

Outcomes

Primary Outcomes

serious infections: meningitis, sepsis, pneumonia, pyelonephritis, osteomyelitis and cellulitis, gastroenteritis with sever dehydration, complicated urinary tract infection and complicated viral airway infection with hypoxia.

Time frame: within 24 hours after assessment