A Study of Danoprevir in Combination With Low-Dose Ritonavir in Healthy Subjects

Inclusion Criteria: * Adult healthy volunteers, 18 - 60 years of age * Female subjects must be surgically sterile or post-menopausal * Male subjects and their partners of child-bearing potential must use to methods of contraception for the duration of the study and for three months after the last drug administration * Agree to abstain from strenuous exercise for three days before dosing and throughout the study (including washout period and follow-up visit) Exclusion Criteria: * History or evidence of any clinically significant disease or disorder * Pregnant or lactating women * Male partners of women who are lactating or trying to become pregnant * Current smokers or subjects who have discontinued smoking less than six months prior to first dosing * Positive alcohol breath test; suspicion of regular consumption of drugs of abuse * Positive for hepatitis B, hepatitis C or HIV infection * Participation in an investigational drug, biologic, or device study within three months before first study drug administration