Experimental intervention: Patient education after lung transplantation via Tablet computers. An electronic patient questionnaire via tablet computer will be collected in addition. Control intervention: Conventional Patient education by health care professionals. A paper-based patient questionnaire will be provided.
Noncompliance with immunosuppressive medications after organ transplantation is thought to be a leading cause of allograft rejection, graft loss, and death. Immunosuppressant medy to prevent graft rejection after lung transplantation. Reported non-compliance rates with calcineurin inhibitors are ranging between 13 and 22 % after lung transplantation. Incidence of non-compliance increases over time after transplantation. Increased health care costs, decreased quality of life, and organ failure (incl. the need for re-do transplantation) are possible consequences of immunosuppressant noncompliance. Therefore, medication compliance defined as the extent to which a patient's medication taking behaviour coincides with the prescribed regimen, is a critical issue in transplantation. Repeated patient education is one option to overcome non-adherence and immunosuppressive medication non-compliance. Immunosuppressive therapy is monitored by measurement of drug levels. Fluctuating drug levels increase the risk for rejection and drug toxicities. In addition, frequent dose adjustments, case management and frequent monitoring of drug levels are cost-intensive.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
64
Patient education by health care professional compared to education via tablet PC
Hanover Medical School
Hanover, Lower Saxony, Germany
Calcineurin trough levels
Improvement of percentage of calcineurin inhibitor trough levels (Delta %) in target range 6 months after patient education compared to 6 months before patient education
Time frame: 6 month
Calcineurin trough levels variability
Trough level variability 6 months after patient education compared to 6 months before patient education
Time frame: 6 month
Interval Adherence
interval adherence (number of measurements vs. recommended measurements) 6 months after patient education compared to 6 months before patient education
Time frame: 6 month
Trough level interval
Interval of trough level measurement variability 6 months after patient education compared to 6 months before patient education
Time frame: 6 month
Total time of education
Total time of education
Time frame: 6 month
Total time of answering questionnaire
Total time of answering questionnaire
Time frame: 6 month
Knowledge Improvement
Improvement of patient knowledge on immunosuppressive after patient education
Time frame: 6 month
Self rated adherence
Self rated adherence to immunosuppressive medication (BAASIS scale)
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Time frame: 6 month
Adherence
Therapy adherence 6 months after patient education compared to 6 months before patient education
Time frame: 6 month
Glomerular filtration rate
Glomerular filtration rate 6 months after patient education compared to baseline (CKD-EPI)
Time frame: 6 month