Virtual Reality for Neglect Diagnostics

Charite University, Berlin, Germany27 enrolled

Overview

Compared to the classical "paper and pencil"-tests, testing patients in our virtual reality setup might have a higher sensitivity and specificity.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Spatial Neglect Stroke

Interventions

virtual reality setupBEHAVIORAL

testing for neglect in a virtual reality setup

paper and pencil testsBEHAVIORAL

testing for neglect with the classical paper-and-pencil tests

c-mriOTHER

structural and functional (resting state) imaging

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria for neglect patients: * age ≥18 and \<80 years * first stroke * neglect symptoms * no hemianopsia symptoms * consent given by the patient Inclusion Criteria for hemianopsia patients: * age ≥18 and \<80 years * first stroke * no neglect symptoms * hemianopsia symptoms * consent given by the patient Inclusion Criteria for Controls: * age ≥18 and \<80 years * no neurological deficits * informed consent Exclusion Criteria (for all groups): * language comprehension deficits * motor deficits of the upper extremities * cognitive impairments (MMSE \<20 or SKT \>15 or DEMTEC \>12) * depression * seizure disorders * claustrophobia

Locations (1)

Charité University Medicine

Berlin, Germany

Outcomes

Primary Outcomes

Feasibility

Feasibility of the use of a virtual reality setup in the diagnostics of neglect

Time frame: within the first 2 years after stroke

Secondary Outcomes

Sensitivity and Specificity

The diagnostics of neglect via a virtual reality setup is more sensitive and more specific than the standard diagnostics via "paper-and-pencil" Tests

Time frame: within the first 2 years after stroke

mri (functional (resting state) and structural imaging

We hypothesize that there are connectivity-based differences in the different stages of neglect and anatomical and functional connectivity correlates with respect to behavioural impairment.

Time frame: within the first 2 years after stroke

Data from ClinicalTrials.gov

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