Pretreating people with replacement doses of vitamin D will allow them to tolerate Statin medications that have caused muscle pain for them in the past.
Patients who have been unable to tolerate statin medications due to muscle pain will be randomly assigned to receive vitamin D or placebo for 6 weeks before reintroducing their statin medication. The investigators will judge whether vitamin D in the manner administered in the study reduces the myalgia with statins and allows patients to remain on these important medications.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
10,000 IU tablets. 50,000 initial dose, followed by weekly doses of 10,000 IU
Standard Placebo made of Lactose 100 mg
MUHC-Royal Victoria Hospital
Montreal, Quebec, Canada
lack of need to stop statin medication due to myalgia
Ability to tolerate a statin at the same dosage that previously caused the individuals to stop due to myalgia
Time frame: 12 weeks
reduction of visual analog pain score
Time frame: 12 weeks
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