Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections

Inclusion Criteria: * Male or female, 2 months to \< 18 years old. * Presence of ABSSSI warranting initial hospitalization. * Presence of ABSSSI with measurable margins of erythema, that includes deeper and/or extensive soft tissue involvement, or requires significant therapeutic surgical intervention Exclusion Criteria: * Documented history of any hypersensitivity or allergic reaction to vancomycin, aztreonam, or any β-lactam antimicrobial * Uncomplicated skin and soft tissue infections * More than 24 hours of prior antimicrobial therapy ≤ 96 hours before randomization. * Requirement for any concomitant systemic antimicrobial therapy * History of seizures, excluding well-documented febrile seizure of childhood. * Clinical signs or suspicion of meningitis