NSAIDs in Coronary Artery Disease Patients

Heinrich-Heine University, Duesseldorf85 enrolled

Overview

Introduction: Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment. Methods: Light-Transmission aggregometry Hypothesis: Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.

Study Type

OBSERVATIONAL

Enrollment

Conditions

CAD

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients on a simultaneous ASA, NSAID treatment * \> 18 years Exclusion Criteria: * unconsciousness, not able to consent * reanimation, cardiac shock

Locations (1)

Heinrich-Heine-University

Düsseldorf, North Rhine-Westphalia, Germany

Outcomes

Primary Outcomes

Thromboxane-levels and light-transmission aggregometry in response to arachidonic acid

Time frame: During hospital stay

Data from ClinicalTrials.gov

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