Pilot Study of a Dietary Intervention Based Upon Advanced Glycation End Products

Inclusion Criteria: * 50 years or older and less than 70 years of age * Non-smoker * Body mass index of 18.5 to \<30 mg/kg2 Exclusion Criteria: * Diabetes, thyroid disease, angina, myocardial infarction, heart failure, stroke, peripheral artery disease, chronic obstructive pulmonary disease, inflammatory bowel disease, liver disease, chronic kidney disease, or Raynaud's disease * Taking regular vitamin supplements, or if taking regular vitamin supplements, not willing to discontinue taking vitamin supplements while participating in the study * Taking vitamin B6 (pyridoxamine) supplements (50 mg or more) * Taking aspirin or nonsteroidal anti-inflammatory medications (NSAIDS), or if so, not willing to discontinue taking aspirin or NSAIDS while participating in the study * Major food allergies (i.e., dairy, nuts, etc) * History of eating disorders or other dietary patterns that are not consistent with the dietary intervention (e.g. vegetarians, very low fat diets, high protein diets) * Loss of 10% of body weight within the last 12 months or plan to initiate a weight loss program during the next two months * Self-report of alcohol or substance abuse with the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in Alcoholics Anonymous is not an exclusion) * Other medical, psychiatric, or behavioral factors that in the judgment of the study doctor may interfere with study participation or the ability to follow the intervention protocol * Not willing to consume the diets being tested by the study * Cognitive impairment, indicated by a Mini-Mental State Exam score \<23 * Triglycerides \>300 mg/dL * Hemoglobin ≤11 g/dL * Creatinine greater or equal to 1.5 mg/dL * Fasting plasma glucose \>125 mg/dL * Proteinuria * Long fingernails on the index finger of each hand, or if so, not willing to trim these two fingernails so that peripheral arterial tonometry can be conducted during the study * Not willing to give written, informed consent to participate in the study * Women who are lactating or pregnant, or plan to become pregnant during the study