Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation

Ramathibodi Hospital86 enrolled

Overview

This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.

Continuous positive airway pressure (CPAP) is widely used in providing ventilator support. However, its role in an acute asthmatic attack is uncertain. The purpose of this study was to compare the efficacy of CPAP when used in addition to conventional therapy with conventional therapy alone in the management of acute asthma exacerbation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Acute Asthma

Interventions

Continuous positive airway pressureDEVICE

CPAP 8 cmH2O

Eligibility

Sex: ALLMin age: 19 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * aged over 18 years * known asthmatic patients visiting ED with acute exacerbation * had given their written informed consent. Exclusion Criteria: * smoking history * chronic obstructive pulmonary disease * required intubation * instability of hemodynamic or arrhythmia * unable to perform PEFR * facial abnormality * pulmonary infiltration * pregnancy.

Locations (1)

Ramathibodi Hospital

Bangkok, Thailand

Outcomes

Primary Outcomes

an improvement in PEFR, as % predicted

Time frame: 75 mins

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.