This study is to assess the pharmacokinetic interaction between ASP1941 and Mitiglinide calcium hydrate in healthy volunteers.
This will be a randomized, open label, four group, two-way crossover design study to assess the effect of drug interaction between ASP1941 and Mitiglinide calcium hydrate on the pharmacokinetics of them after separate and concomitant administration to healthy non-elderly adult male subjects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
60
oral
oral
Unnamed facility
Kantou, Japan
Pharmacokinetics of ASP1941 and Mitiglinide calcium hydrate assessed by its plasma concentration change
Time frame: For up to 72 hours after each administration
Safety assessed by incidence of adverse event, vital signs, 12-lead ECG and laboratory tests
Time frame: For up to 10 days
Pharmacokinetics of the metabolites of ASP1941 assessed by its plasma concentration change
Time frame: For 72 hours after ASP1941 administration
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