The main objective of this study was to evaluate the effect of intermittent pneumatic venous compression on intra-operative fluid intake by comparing two groups of patients with or without intermittent pneumatic compression of the lower limbs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Intermittent pneumatic venous compression is applied to the lower limbs of patients during surgery.
Intermittent pneumatic venous compression is not applied to the lower limbs of patients during surgery.
Centre Hospitalier Universitaire de Nîmes
Nîmes, Gard, France
Volume fluids (ml)
The total volume of infused fluids (Ringer's Lactate and HES) delivered to the patient during surgery (ml)
Time frame: End of surgery (expected mean of 2 hours)
Hypotensive episodes
The number of arterial hypotension episodes (systolic pressure \< 90 mmHg)
Time frame: end of surgery (expected mean of 2 hours)
VEGF
Concentration (pg/ml) of Vascular Endothelial Growth Factor (VEGF) in blood
Time frame: end of surgery (expected mean of 2 hours)
sFlt1
Concentration (pg/ml) of soluble vascular endothelial growth factor receptor-1 (sFlt1) in blood
Time frame: end of surgery (expected mean of 2 hours)
Hematocrit %
Time frame: end of surgery (expected mean of 2 hours)
Albumin
Albuminemia (g/l)
Time frame: end of surgery (expected mean of 2 hours)
Prothrombin (%)
Prothrombin rate in blood
Time frame: end of surgery (expected mean of 2 hours)
Activated partial thromboplastin time
Activated partial thromboplastin time (seconds)
Time frame: end of surgery (expected mean of 2 hours)
Presence/absence of POSSUM complications
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Presence/absence of complications as defined by the Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM) criteria
Time frame: 28 days
Days of hospitalization
Length of hospitalization (days)
Time frame: 28 days
Number of days not in hospital
Number of days not in hospital
Time frame: 28 days