The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.
The management of chronic eye pain is a constant challenge to ophthalmology. Treatment varies with the intensity of pain, and topical eye drops and contact lens therapy are effective in many patients. In refractory cases, and without vision, surgical removal of the eye through enucleation is considered classical therapy. As less invasive alternatives we have cyclodestruction and neurolytic drug injection in order to promote analgesia for a prolonged period. The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of This is a prospective study of patients with blind painful eyes not responsive to topical treatment and with no indication for evisceration seen at the Department of Ophthalmology, Hospital Governador Celso Ramos (HGCR) in 2010.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
36
0,3mL intravitreal injection of Triamcinolone, single dose
2,5mL Chlorpromazine retrobulbar injection, single dose
Hospital Governador Celso Ramos
Florianópolis, Santa Catarina, Brazil
Changes in Pain intensity
Pain was measured asking the patient to graduate it in a scale from 0 to 10, 0 being no pain, 10 being the worst pain patient has experienced in life
Time frame: 0, 1 month, 3 months, 6 months after procedure
Changes in Use of eyedrops before and after drug injection
Patient use of eyedrops before and after the procedure (yes or no)
Time frame: 0, 1 month, 3 months, 6 months
Changes in Intraocular pressure (IOP)
IOP was measured at all times of patient evaluation
Time frame: 0, 1 months, 3 months, 6 months
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