Budesonide Application Via Mucosal Atomization Device as a Treatment for Chronic Rhinosinusitis When Utilized as a Topical Nasal Steroid Spray

Inclusion Criteria: * 19 years of age or older * Diagnosed with CRS with or without polyps * Awaiting for Functional Endoscopic Sinus Surgery * Give consent on their own Exclusion Criteria: Concurrent or recent use (within the past 30 days) of systemic corticosteroids * History of pituitary disease * Morbid obesity (body mass index \[calculated as weight in kilograms divided by height in meters squared\] * Concurrent or recent use of medications that accelerate the clearance of cortisol: o Such as dilantin, rifampin, amphetamines, or lithium carbonate * Concurrent use of medications that interfere with the production of cortisol: o Such as ketoconazole, amphotericin B, bupropion, Echinacea, fluoroquinolones, itraconazole, licorice * Use of oral contraception * Use of female or male hormone therapy * Known hypersensitivity to cortisol, corticotropin, or cosyntropin