The purpose of this study is to investigate the effect that obesity may have on the nonsurgical treatment (with and without the adjunct use of metronidazole) of destructive periodontal diseases (chronic periodontitis).
Normal weight (BMI 18.5-24.9 kg/m2) and obese (BMI \>30 kg/m2) women will be randomly assigned to two nonsurgical periodontal treatments: 1. scaling and root planing + placebo 2. scaling and root planing + metronidazole
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
96
Metronidazole 400mg TID for 10 days
Placebo pill TID for 10 days
Scaling and root planning performed with curettes and ultrasonic scalers under local anesthesia
Universidade Federal do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, Brazil
RECRUITINGProbing depth
Defined as the distance from the free gingival margin to the bottom of the pocket/sulcus.
Time frame: 12 months
Attachment level
Defined as the distance from the CEJ to the bottom of the pocket/sulcus.
Time frame: 12 months
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