PEEK and Allograft Spacers Evaluation in Spinal Fusion Surgeries

Lumbar Fusion Patient Group Inclusion Criteria: * Skeletally mature adults between 18 and 70 years old * Patients with back and leg pain due to degenerative disc disease, scheduled for TLIF/PLIF approach utilizing an interbody spacer and supplemental posterior fixation at 1, 2 or 3 adjacent levels * Unresponsive to conservative care over a period of at least 6 months or has progressive neurological signs and/or symptoms of neurological compromise that mandate urgent surgical intervention * Willing and able to comply with the requirements of the protocol including followup requirements * Willing and able to sign a study specific informed consent. Exclusion Criteria: * More than 3 intervertebral levels to be fused * Posterior fixation used at more than 1 level for 1-level intervertebral fusion * Posterior fixation used at more than 2 levels for 2-level intervertebral fusion * Posterior fixation used at more than 3 levels for 3-level intervertebral fusion * Any additional approaches, e.g. anterior, XLIF * Active local or systemic infection * Prior interbody fusion surgery at the index level * Prior fusion at the adjacent levels * Previous known allergy to polyetheretherketone (PEEK) or titanium alloy Cervical Fusion Patient Group Inclusion Criteria: * Skeletally mature adults between 18 and 70 years old * Patients with neck and/or arm pain due to degenerative disc disease, scheduled for ACDF approach utilizing an interbody spacer and anterior cervical plate at 1, 2 or 3 adjacent levels * Completed at least 6 weeks of conservative therapy or has progressive neurological signs and/or symptoms of neurological compromise that mandate urgent surgical intervention * Willing and able to comply with the requirements of the protocol including followup requirements * Willing and able to sign a study specific informed consent Exclusion Criteria: * More than 3 vertebral levels to be fused * Any additional approaches, e.g. posterior cervical fusion * Active local or systemic infection * Prior interbody fusion surgery at the index level * Prior fusion at the adjacent level * Previous known allergy to polyetheretherketone (PEEK) or titanium alloy