Combined Effects of Energy Density and Eating Rate on Appetite

United States Army Research Institute of Environmental Medicine20 enrolled

Overview

This study will examine the independent and combined effects of energy density and eating rate on appetite and endocrine mediators of appetite. Increasing eating rate and energy intake are expected to additively increase energy intake.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Appetite

Interventions

Eating rateBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI 18-27 kg/m2 * Weight stable Exclusion criteria: * Chronic used of OTC or prescription drugs known to affect metabolism * Chronic disease * Gastric bypass surgery * Disordered eating * Pregnant or breastfeeding

Locations (1)

USARIEM

Natick, Massachusetts, United States

Outcomes

Primary Outcomes

Energy intake

Time frame: 1 meal

Secondary Outcomes

Subjective appetite

Time frame: 0-180 min

Postprandial peptide-YY response

Time frame: 0-180 min

Postprandial ghrelin response

Time frame: 0-180 min

Postprandial glucagon-like peptide-1 response

Time frame: 0-180 min

Postprandial pancreatic polypeptide response

Time frame: 0-180 min

Data from ClinicalTrials.gov

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