Safety and Efficacy of Glucosanol in Reducing Body Weight in Overweight and Obese Subjects

Inclusion Criteria: * Age 18 to 60 years * BMI between 25 and 35 * Expressed desire for weight loss * Accustomed to 3 main meals/day * Consistent and stable body weight 3 months prior to study enrolment * Commitment to avoid the use of other weight loss products during study * Commitment to adhere to diet recommendation * Females' agreement to use appropriate birth control methods during the active study period * Subject declares in writing his/her consent to participate, understands requirements of the study and is willing to comply Exclusion Criteria: * Known sensitivity to the ingredients of the device * History of Diabetes mellitus * Fasting blood glucose \>7 mmol/L * History or clinical signs of endocrine disorders which may influence body weight (e.g., Cushing's disease, thyroid gland disorders) * Clinically relevant excursions of safety parameter * Current use of anti-depressants * Presence of acute or chronic gastrointestinal disease (e.g., IBD, coeliac disease. pancreatitis) * Uncontrolled hypertension (\>160/110 mm Hg) * Stenosis in the GI tract * Bariatric surgery * Abdominal surgery within the last 6 months prior to enrollment * History of eating disorders such as bulimia, anorexia nervosa within the past 12 months * Other serious organ or systemic diseases such as cancer * Any medication that could influence GI functions such as antibiotics, laxatives, opioids, glucocorticoids, anticholinergics, or antidiarrheals (e.g., loperamide; must have stopped 1 months before study start) * Pregnancy or nursing * Any medication or use of products for the treatment of obesity * More than 3 hours strenuous sport activity per week * History of abuse of drugs, alcohol or medication * Smoking cessation within 6 months prior to enrolment * Inability to comply due to language difficulties * Participation in similar studies or weight loss programs within 3 months prior to enrolment * Participation in other studies within 4 weeks prior to enrollment