Immunogenicity and Safety of AdimFlu-S 2011-2012 in Non-Elderly Adult and Elderly Subjects

Inclusion Criteria: * Males or non-pregnant females and aged ≥ 18 years; * Willing and able to adhere to visit schedules and all study requirements; * Subjects read and signed the study-specific informed consent. Exclusion Criteria: * Subject or his/her family is employed by the participated hospital; * Subjects received 2010-2011 seasonal influenza vaccine within the previous 6 months; * History of hypersensitivity to eggs or egg protein or similar pharmacological effects to study medication * Personal or family history of Guillain-Barré Syndrome * An acute febrile illness within 1 week prior to vaccination; * Current upper respiratory illness, including the common cold or nasal congestion within 72 hours * Subjects with influenza-like illness as defined by the presence of fever (temperature ≥ 38°C) and at least two of the following four symptoms: headache, muscle/joint aches and pains (e.g. myalgia/arthralgia), sore throat and cough * Female subjects who are pregnant during the study * Treatment with an investigational drug or device, or participation in a clinical study, within 3 months before consent * Immunodeficiency, or under immunosuppressive treatment * Receipt of any vaccine within 1 week prior to study vaccination or expected receipt between Visit 1 (study vaccination) and Visit 2 (final collection of blood samples); * Receipt of any blood products, including immunoglobulin in the prior 3 months; * Underlying condition in the investigators' opinion may interfere with evaluation of the vaccine