Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

Medical University of Vienna16 enrolled

Overview

The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

Methods: microdialysis, blood sampling, bronchoalveolar lavage

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pneumonia Abdominal Infection Urinary Tract Infection

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection Exclusion Criteria: * allergy to doripenem, hemodialysis

Locations (1)

Med. Univ. of Vienna

Vienna, Austria

Data from ClinicalTrials.gov

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