The purpose of this study is to evaluate the efficacy of an active rehabilitation program on disability and quality of life of patients affected by dermatomyositis and polymyositis.
Dermatomyositis (DM) and polymyositis (PM) are inflammatory disabling neuromuscular disorders. Despite partial benefit of pharmacological treatments, muscle strength, functional status and quality of life remain impaired. Although the use muscle exercises in (DM) and (PM) have been reported, its efficacy on disability and quality of life has not been proved. Te aim of the study is to evaluate the benefit at mid term (12 months) of an active rehabilitation program administrated to patients affected by PM and DM. Method: a 3 year prospective, multicentric, randomized controlled trial A program of 12 individual exercise sessions (3 per week during 4 weeks) is compared to conventional care. Patients are followed 12 month after the inclusion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
80
A program of 12 individual exercise sessions (3 per week during 4 weeks)
University Hospital, Lille
Lille, Hauts-de-France, France
Hopital Rotschild
Paris, France
GH Pitié Salpétrière
Paris, France
Hopital Cochin
Paris, France
Centre hospitalier universitaire de Rouen
HAQ score
Time frame: 6 month and 1 year after rehabilitation
Quality of life (SF36 score)
Time frame: 6 month and 1 year after rehabilitation
MFM(motor function measure)
Time frame: 6 month and one year after rehabilitation
muscle strength (MRC manual muscle testing)
Time frame: at 6 month and one year after rehabilitation
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Rouen, France