The aim of this clinical trial is to evaluate the antitussive effect of "Theobromine capsule 300mg" in patients with acute bronchitis.
This study is double blinded, randomized, parallel designed, phase III clinical trial to evaluate the efficacy and safety of "Theobromine capsule 300mg" versus "Levodropropizine syrup" in patients with acute bronchitis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
332
Capsule, b.i.d.
Syrup, t.i.d.
Hallym University Medical Center
Anyang-si, Gyeonggi-do, South Korea
cough remission rate
cough remission : no cough or 1 short cough in day time
Time frame: 3 days
cough recovery rate
Time frame: 1 day, 2 days, within 3days
difference of DCS score between screening and closing visit.
Time frame: 3 days
required time for cough remission
Time frame: 3 days
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