Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies

National University Hospital, Singapore

Overview

The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.

Study Type

OBSERVATIONAL

Conditions

Combat Training Stress

Eligibility

Sex: MALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises. Exclusion Criteria: * Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus. * No written informed consent obtained from subject.

Data from ClinicalTrials.gov

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