The prevalence of NAFLD is 50-70% in obese people. A decrease of calorie intake and increase of physical activity are recommended as an effective approach for the prevention and treatment of NAFLD. However, the exercise model for NAFLD intervention is understudied. In the present study we aim to compare the effect of intensive and conventional exercise interventions on NAFLD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
220
Subjects conduct an aerobic exercise at 65-80% maximum oxygen consumption for 30 minutes each day, five days a week, totally for 6 months.Subsequently, moderate physical activity(3.0-6.0 MET s) at 150 min/wk for 6 months.
Subjects receive moderate physical activity(3.0-6.0 MET s) at 150 min/wk(30 min per day, five days a week) for 12 months.
The First Hospital Affiliated to Xiamen University
Xiamen, China
Change of intrahepatic triglyceride contents
Time frame: 12 months
Change of body weight
Time frame: 12 months
Change of waist circumference
Time frame: 12 months
Change of body fat
Time frame: 12 months
Change of abdominal fat
Time frame: 12 montshs
Change of carotid intima-media thickness
Time frame: 12 months
Change of cardiovascular risk factors (Blood pressure, lipids, glucose)
Time frame: 12 months
Change of insulin resistance
Time frame: 12 months
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