Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder

Inclusion Criteria: * 7 to 17 year old with diagnostic and statistical manual of mental disorders, fourth edition -text revision (DSM-IV-TR) diagnostic criteria for Tourette's disorder (TD), confirmed by the kiddie schedule for affective disorders and schizophrenia - present and lifetime version (K-SADS-PL), including the Diagnostic Supplement 5 * Has a total tic score (TTS) ≥20 on the yale global tic severity scale (YGTSS) at Screening and Baseline * Presenting tic symptoms cause impairment in the participant's normal routines, which include academic achievement, occupational functioning, social activities, and/or relationships * Females of childbearing potential must have a negative pregnancy test, must be practicing acceptable double-barrier methods of contraception, and must not be pregnant or lactating. * Written informed consent form (ICF) obtained from a legally acceptable representative \& informed assent at Screening as applicable by study center's Institutional review board/independent ethics committee (IRB/IEC) * The participant, designated guardian(s) or caregiver(s) are able to comprehend and satisfactorily comply with the protocol requirements, as evaluated by the investigator. Exclusion Criteria: * Clinical presentation and/or history, consistent with another neurologic condition that may have accompanying abnormal movements. * History of schizophrenia, bipolar disorder, or other psychotic disorder. * Participant receiving psychostimulants for treatment of attention-deficit disorder/Attention-deficit hyperactivity disorder (ADD/ADHD) and who have developed and/or had exacerbations of tic disorder after initiation of stimulant treatment. * Currently meets DSM-IV-TR criteria for a primary mood disorder. * Severe obsessive-compulsive disorder (OCD), per children's yale-brown obsessive compulsive scale (CY-BOCS) score \>16. * Taken aripiprazole within 30 days of the Screening visit. * Received any investigational agent in a clinical trial within 30 days prior to Screening or who were randomized into a clinical trial with Once-weekly aripiprazole at any time. * History of neuroleptic malignant syndrome. * Sexually active participants not using 2 approved methods of contraception; breastfeeding or pregnant. * Risk of committing suicide * Bodyweight lower than 16 kg * Taken neuroleptic or antiparkinson drugs \<14 days prior to randomization. * Requiring cognitive-behavioral therapy (CBT) for TD during study. * Participant meets DSM-IV-TR criteria for any significant psychoactive substance use disorder within the past 3 months. * Positive drug screen * Participant requires medications not allowed per protocol * Use of CYP2D6 and CYP3A4 inhibitors or CYP3A4 inducers within 14 days prior to dosing and for duration of study. * Inability to swallow tablets or tolerate oral medication * Abnormal laboratory test results, vital signs and Electrocardiogram (ECG) results