Renal Sympathetic Modification in Patients With Chronic Renal Failure

Inclusion Criteria: * ≥ 18 years old, and ≤ 75 years old of age * at least three months history of definite kidney damage * renal function of serum creatinine of \< 354umol/L, and/or creatinine clearance rate of ≥ 30ml/min, and/or estimated glomerular filtration rate of ≥ 45ml/min for recent 2-3 times evaluation. Besides, the value of creatinine clearance rate fluctuated no more than 30% in recent three months, and 15% in the following two weeks. * urine microalbumin, and/or urine microalbumin/creatinine is abnormal, and/or quantity of 24 hrs urine protein suggests kidney damage. * is competent and willing to provide written, informed consent to participate in this clinical study Exclusion Criteria: * congenital renal diseases cause to chronic renal damage * estimated glomerular filtration rate (eGFR) of \< 45mL/min * taking medicine of glucocorticosteroids, non-steroid anti-inflammatory drugs (NSAIDs), or cytotoxic drugs at present * value of 24 hrs urine protein is of \> 10g at least once in recent three months, or serum albumin of \< 25g/L * has the history of renal restenosis or renal stents implantation * has experienced AMI (old myocardial infarction is not excluded), unstable angina pectoris, cerebrovascular accidents, and alimentary tract hemorrhage within 3 months * carcinoma patients * patients with sick sinus syndrome * pregnant women * mental disorders * patients that have allergy to contrast agent * patients that do not go with follow-up * others such as researcher considers it is not appropriate to be included into the study