The objective of the study is to show post-prandial benefits of Palaeolithic-type meals as compared to a meal constructed along the lines of the WHO dietary recommendations.
The effects of this set of meals will be assessed with respect to blood * blood glucose * plasma insulin * satiety scores * plasma gut hormones It is hypothesised that lower post prandial blood glucose concentration, a lower insulin response and increased satiety will be seen after the Palaeolithic meals compared with a reference meal
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
24
Based on estimated ratios for protein, fat and carbohydrates that are typical of Hunter-Gatherers and does not contain ingredients that were not available in pre-neolithic times
Based on WHO dietary guidelines for protein, fat and carbohydrate but does not contain ingredients that were not available in pre neolithic times
Based on WHO dietary guidelines for protein, fat and carbohydrate.
Leatherhead Food Research
Leatherhead, Surrey, United Kingdom
Blood glucose
positive incremental area under the concentration versus time
Time frame: 0-2 hours
Plasma insulin
net incremental area under the curve
Time frame: 0-2 hours
Peak blood glucose
maximal blood glucose value
Time frame: 0-2 hours
Satiety scores
area under the curve
Time frame: 0-2 hours
Gut hormone panel
Average concentration over time
Time frame: 0-3 hours
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