RadIal Versus Femoral InvEstigation in ST Elevation Acute Coronary Syndrome

Inclusion Criteria: 1. Subject is \>18 years old with recent acute ST-elevation acute coronary syndrome (STEACS) requiring emergent coronary angiography. 2. Patient has no contraindication to percutaneous arterial access by both and transfemoral route. 3. Subject has been informed of the nature of the study and agrees to its provisions and has provided written informed consent as approved by the Institutional Review Board/Ethics Committee of the respective clinical site. 4. Patient and the treating physician agree that the subject will comply with all follow-up evaluations. Exclusion Criteria: 1. Subject's age is \<18 years and he has no acute ST-elevation myocardial infarction (ST elevation of a least 0.1 mV in ≥2 extremity leads or at least 0.2 mV in ≥2 precordial leads). 2. Subject has had a recent stroke or TIA (\<4 weeks), irrespective of age. 3. Patient has an international normalized ratio (INR) \> 2.0, or other severe bleeding diathesis 4. The patient is pregnant or breastfeeding. 5. Known allergies to: aspirin, clopidogrel and ticlopidine, heparin, IIb/IIIa inhibitors, stainless steel, or contrast agent (which cannot be adequately premedicated). 7.Subject is currently participating in an investigational drug or device study that has not completed the primary endpoint or that clinically interferes with the current study endpoints. 8.Prior participation in this study.