Effect of Intravitreal Bevacizumab on Focal Edema With Hard Exudates Secondary to Diabetic Retinopathy

Inclusion Criteria: 1. patients of either gender aged \> 18 years 2. patients with type 2 diabetes 3. central macular thickness \> 300 µm on OCT 4. eyes not eligible for focal laser photocoagulation due to the central location of hard exudates (\< 500 µm) 5. an area of retinal thickening less than 2 disc areas in diameter 6. 67% or more of leakage associated with microaneurysms Exclusion Criteria: 1. eyes with history of laser photocoagulation or pharmacological intervention for DME on study eye 2. eyes with any pharmacologic intervention on fellow eye within 6 months 3. history of ocular diseases other than diabetic retinopathy 4. surgical history other than cataract extraction with intraocular lens implantation 5. panretinal photocoagulation within 3 months of enrollment 6. media opacity 7. any thromboembolic event within 6 months, or evidence of active cardiac ischemia on electrocardiogram (ECG) at time of screening.