Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension: Prevalence and Quality of Life

Wissenschaftliches Institut Bethanien e.V220 enrolled

Overview

The purpose of this study is to determine the prevalence of pulmonary hypertension (PH) among patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and to assess the quality of life in those patients with concomitant PH compared to COPD patients without PH and those only suffering from pulmonary arterial hypertension (PAH) respectively.

Study Type

OBSERVATIONAL

Enrollment

220

Conditions

Hypertension, Pulmonary Pulmonary Disease, Chronic Obstructive

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Known or newly diagnosed COPD or PAH * Written informed consent * Present long-term oxygen treatment is no exclusion criterion Exclusion Criteria: * Age \< 18 years * Right-heart catheterization not reasonable * Pregnancy, Lactation * Life expectancy \<12 months due to any diseases aside from COPD * Any medical, psychological or other condition, which limits the patient's ability to provide informed consent * No written informed consent provided * Current participation in another clinical trial

Locations (1)

Bethanien Hospital, Clinic for Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Institute for Pneumology at the University Witten/Herdecke

Solingen, North Rhine-Westphalia, Germany

Outcomes

Primary Outcomes

Prevalence of PH

Prevalence of PH as defined by ESC/ERS guidelines (mean pulmonary arterial pressure ≥25 mmHg, assessed by right-heart catheterization) among the subgroup of COPD GOLD III and IV patients.

Time frame: At baseline

Secondary Outcomes

Quality of life

Explorative data analysis to assess correlation between quality of life and PH, by comparison of COPD patients with and without PH and a reference group of patients with only PAH.

Time frame: One year

Data from ClinicalTrials.gov

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