The purpose of this study is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamics of orally administrated DWP10292 in healthy male volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
52
Seoul National University Hospital
Seoul, Korea, South Korea
Seoul National University Hospital
Seoul, South Korea
Composite of Pharmacokinetics
Cmax, AUClast, AUCinf, Tmax, t1/2, CL/F
Time frame: 0 (predose), 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 16, 24 (2d 0h), 36, 48 (3d 0h), 60, 72 (4d 0h), 96 h(5d 0h) and Post study visit 216h (10d 0h)
Safety&tolerability
Adverse events, Physical exam, Vital sign, laboratory(CBC,chemistry,U/A etc)
Time frame: 0 (predose), 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 16, 24 (2d 0h), 36, 48 (3d 0h), 60, 72 (4d 0h), 96 h(5d 0h) Post study visit 216h (10d 0h)
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