Maturation of the Autonomic Nervous System in Prematures

N/ACompletedNCT01423942

Rambam Health Care Campus300 enrolled

Overview

The purpose of this study is to try to evaluate the maturation of the autonomic nervous system in prematures.

To evaluate the maturation of the autonomic nervous system in prematures by using heart rate variability analyses.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Analysis, Event History

Eligibility

Sex: ALLMin age: 1 DayMax age: 100 DaysHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All prematures

Locations (1)

RMC

Haifa, Israel

Outcomes

Primary Outcomes

Herat rate variability (HRV) characteristics

It is well known that maturation of the autonomic nervous system can be detected by heart rate variability in children. The purpose of this study is to apply HRV characteristics in premature infants and try to evaluate if there are noticable changes in these parameters both in "healthy" and diseased premature infants longitudinally during their stay at the NICU. Outcome measures to be studied are very low frequency ( VLF), low-frequency ( LF), high frequency (HF) frequency bands in the power spectrum density (PSD) of HRV records.

Time frame: 3 years

Data from ClinicalTrials.gov

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