Effect of Moderate Alcohol Consumption on Postprandial Mood

Inclusion Criteria: * Healthy as assessed by the health and lifestyle questionnaire, (P9334 F02; in Dutch) * Females aged 18-45 years at Day 01 of the study * Taking a monophasic combined oral contraceptive pill at Day 01 of the study, with 21 days of taking pills with active ingredients followed by 7 days taking no pills or continuous intake of the oral contraceptive pill * Body Mass Index (BMI) of 18.5-27 kg/m2 * Body weight between 57 and 80 kg * Normal Dutch eating habits as assessed by P9334 F02 * Alcohol consumption ≥ 3 and ≤ 21 standard units/week * Voluntary participation * Having given written informed consent * Willing to comply with the study procedures, including refrain from alcohol 24 h before the test days and refrain from caffeine during the afternoon of the test day * Appropriate veins for blood sampling/cannula insertion according to TNO * Willing to accept use of all nameless data, including publication, and the confidential use and storage of all data for at least 15 years * Willing to accept the disclosure of the financial benefit of participation in the study to the authorities concerned Exclusion Criteria: * Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study. * Having a history of medical or surgical events or disease that may significantly affect the study outcome, particularly physiological disorders, or psychiatric, metabolic or endocrine disease and gastrointestinal disorders. * Use of medication that may affect the outcome of the study parameters (e.g. antidepressive drugs). * Having a family history of alcoholism * Having a history of alcohol or drug related problems * Smoking * Reported unexplained weight loss or gain of \> 2 kg in the month prior to the pre-study screening * Reported slimming or medically prescribed diet * Reported vegan, vegetarian or macrobiotic * Recent blood donation (\<1 month prior to the start of the study) * Not willing to give up blood donation during the study. * Pregnant (to their own knowledge) or lactating or wishing to become pregnant in the period of the study * Personnel of TNO Zeist, their partner and their first and second degree relatives * Not having a general practitioner * Not willing to accept information-transfer concerning participation in the study, or information regarding her health, like laboratory results, findings at anamnesis or physical examination and eventual adverse events to and from his general practitioner.