The aim of the present study is to evaluate the efficacy and safety of two dose combination of Telmisartan/S-Amlodipine (40/2.5mg and 40/5mg) compared with telmisartan monotherapy (80mg) in hypertensive patients inadequately controlled by telmisartan monotherapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
183
Fixed dose combination of Telmisartan 40mg and S-Amlodipine 2.5mg
Fixed dose combination of Telmisartan 40mg and S-Amlidioine 5mg
Telmisartan 80mg monotherapy
Kandong Sacred Heart Hospital
Anyang, South Korea
Daegu Catholic University Medical Center
Daegu, South Korea
Mean Sitting Diastolic Blood Pressure (MSDBP)
Time frame: After 8 weeks of treatment
Mean Sitting Diastolic Blood Pressure (MSDBP)
Time frame: After 4 weeks of treatment
Mean Sitting Systolic Blood Pressure (MSSBP)
Time frame: After 4 weeks and 8 weeks of treatment
Response rate
Reduction of SBP ≥ 20mmHg, DBP ≥ 10mmHg
Time frame: After 4 weeks and 8 weeks of treatment
Control rate
Reduction SBP \< 140mmHg, DBP \< 90mmHg
Time frame: After 4 weeks and 8 weeks of treatment
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