Pharmaco-economic Study of a New Medical Device Performed From the Perspective of the Hospital

Inclusion Criteria: * Patients \> 18 years Patient receiving: * Conditioning of autologous bone marrow transplantation by high dose melphalan (HD) as part of the management of myeloma or BEAM in lymphoma. * A conditioning allogeneic bone marrow transplantation with reduced or intermediate busulfan IV * Patients belong to a schema of social security, having signed the written informed consent. Exclusion Criteria: * patients: * To receive or have received KGF * With previous history of RT with the exception of patients who received spinal analgesic therapy in the treatment of myeloma * Unable or unwilling to complete the self assessment questionnaire * With previous history of allergy to any component of the products under consideration * Minor * Adults under guardianship * Pregnant women * Patients who have not signed the consent form * Creation of mouthwash out of the study