The objective of the current study is to determine the acute effect of a glucose drink and a sacharose drink compared to a placebo on cognitive performance in elderly with light memory complaints. The investigators expect that the sugar containing drinks will improve memory and attentional functions. Furthermore, blood glucose response will be measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
DOUBLE
Enrollment
43
The effect of a glucose solution on cognitive performance will be measured.
The effect of a sacharose solution on cognitive performance will be measured.
The effect of a placebo drink with sweeteners on cognitive performance will be measured.
Wageningen University
Wageningen, Gelderland, Netherlands
Performance on the paired associate recall test
Cognitive performance will be assessed by several sensitive tests. Power is calculated on the paired associate recall test, but also several other cognitive performance test focusing on memory, attention and reaction time will be performed
Time frame: cognitive tests will start 15 minutes after ingestion of the intervention product
Mood
Mood will be measured by the POMS, after consuming the test drink, and after completing the congitive tests.
Time frame: within 15 minutes after consuming the test drink and after completing the cognitive tests (within 90 minutes after consuming the test drink)
Blood glucose response
Blood glucose will be measured at five time points, at t=0, after 15 minutes, 30, 60 and 90 minutes.
Time frame: from baseline till 90 minutes after consuming the drink
Plasma insulin levels
One venapunction will be carried out at baseline to measure plasma insulin levels.
Time frame: At t= -15 minutes, before consuming the test drink
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