The purpose of this study is to compare the ability of Aquacel® Ag and Mepilex® Border Ag to manage bioburden in leg ulcers over a two week study period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Dressing will be changed during the clinic visit on day 3, 7 and 14. In between the clinic visits the dressing should be changed when needed depending on the clinical condition of the wound and the volume of exudate.
Dressing will be changed during the clinic visit on day 3, 7 and 14. In between the clinic visits the dressing should be changed when needed depending on the clinical condition of the wound and the volume of exudate.
The Willows Centre for Health Care
Weaste, Salford, United Kingdom
Wound Healing Research Unit, Cardiff University
Cardiff, Wales, United Kingdom
Arrowe Park Hospital
Upton, Wirral, United Kingdom
Microbial load reduction
The relative reduction from baseline in microbial load (bio-burden) over a 2 week study period as measured by quantitative and qualitative microbiology methods.
Time frame: Days 1 and 14
clinical evolution of the wound (presence of each of the selected clinical signs)
Study's clinical signs: level of exudate (moderate or heavy at baseline), pain between 2 dressing changes, peri-ulcer skin erythema, oedema, foul odour
Time frame: Days 1, 3, 7, 14
Occurrence of adverse events
Time frame: Day 1-14
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