Berlin Beat of Running Study

Charite University, Berlin, Germany110 enrolled

Overview

This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.

Up to 120 experienced marathon runners will participate in the "Berlin Beat of Running Study" and will wear a transportable electrocardiogram (ECG) recorder at least 24 hours before, during and 24 hours after the BMW-Berlin Marathon. All participants will undergo brain MRI examinations to detect cerebral lesions within days before and after the marathon race, respectively. Moreover, serial blood samples will be taken a few days before, immediately after as well as a few days after the BMW-Berlin Marathon.

Study Type

OBSERVATIONAL

Enrollment

110

Conditions

Cardiac Arrhythmia Brain Lesion Stroke

Eligibility

Sex: ALLMin age: 35 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 35-65 years * at least 2 marathon runs within the last 5 years * weekly running of at least 40 km Exclusion Criteria: * Known cardiac arrhythmia or prior stroke * contraindication for MRI.

Locations (1)

Center for Stroke Research Berlin

Berlin, Germany

Outcomes

Primary Outcomes

Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording

During ECG recording

Time frame: Up to 48 hours after the marathon race.

Secondary Outcomes

Rate of (clinically silent) cerebral lesions detected by 3 Tesla brain MRI.

Up to 3 days after marathon.

Time frame: 3 days

Data from ClinicalTrials.gov

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