The purpose of the study is to study if coronary angiography cause cognitive dysfunction.
We have previously shown, using transcranial doppler, that coronary angiography cause cerebral microembolism. Cerebral microemboli were more common using the radial than femoral approach. Previously, cerebral microembolism has been associated with new cerebral lesions on MRI. The clinical significance of these new lesions is not determined. The primary aim of this pilot study is to see if coronary angiography cause cognitive dysfunction determined by the MoCA-test. A secondary aim is to relate cognitive dysfunction to cerebral microembolism measured by transcranial doppler. A third aim is to study potential differences between the femoral and radial approaches.
Study Type
OBSERVATIONAL
Enrollment
80
Randomization to right radial or femoral approach
Cardiology Clinic, Karolinska University Hospital
Stockholm, Sweden
Change in cognitive dysfunction from baseline to two days after coronary angiography
The Montreal Cognitive Assesment test will be performed before, 2 and 30 days after coronary angiography
Time frame: Baseline and two days
Number of patients with cerebral microemboli
Cerebral microembolism will be studied by transcraniell doppler at the time of angiography. Findings will be related to change in cognitive function between baseline and two days.
Time frame: Baseline
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