The aim of this trial is compare two different endometrial priming protocols * women that receive oral estrogens * women that receive transdermal estrogens
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
140
2 mg of estradiol every day beginning the second day of the cycle until day 7. 4 mg of estradiol every day beginning 8th day of the cycle until day 10. 6 mg of estradiol every day beginning 11th day of the cycle until day 16.
One patch of 75 mcg of estradiol hemimydrate every 48 h from 2 to day 6. Two patches of 75 mcg of estradiol hemimydrate every 48 h from 6 to day 12. Three patches of 75 mcg of estradiol hemimydrate every 48 h from 12 to day 16.
Hospital del Mar
Barcelona, Spain
Difference between day means in endometrial priming to achieve 7 mm.
Time frame: 11-16 days
Biochemical Pregnancy rate
To calculate the biochemical pregnancy rate, we will divide the number of biochemical pregnancy into the number of embryonary transference and multiply by 100.
Time frame: 26-30 days
The patient's adherence to the recommended treatment.
Time frame: 1-16 days
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