Effect of Temperament, Anxiety and Depression on Immuninity in Colorectal Cancer Patients. Effetti Del Temperamento, Dell'Ansia e Della Depressione Sulla Sopravvivenza Globale e Sulla Risposta Immunitaria Del Paziente Affetto da Adenocarcinoma Colo-Rettale.

University of Roma La Sapienza120 enrolled

Overview

Aim of the study is to evaluate if Temperament, Anxiety and Depression can affect Immunity and influence Survival in Colorectal Cancer Patients

120 prospective patients, with non-metastatic colorectal cancer, will be evaluated with questionnaires and auto-questionnaires in order to assess temperament, anxiety and depression. The immunity status will be assessed by a blood sample with the aim to evaluate cell-mediated immunity. Survivall will be related to level of anxiety/temperament/depression and cell-mediated immunity. Univariate and multivariate model analisys will be performed in order to evaluate if anxiety/temperament/depression and cell-mediated immunity can be considered as prognostic factors.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Temperament Anxiety Depression Colorectal Cancer

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: diagnosis of non-metastatic colorectal cancer Exclusion Criteria: previous other primary malignancies immunodepression diagnosis of major deppression diagnosis of anxiety/depression syndrome

Outcomes

Primary Outcomes

Temperament in non-metastatic colorectal cancer patients

Evaluation if Temperament can be considered as dependent or indipendent prognostic factor for survival in non-metastatic colorectal cancer patients

Time frame: 24 months