Dual-energy Contrast-enhanced (2D and 3D Mammography Versus Contrast-enhanced MRI)- A Pilot Study

Inclusion Criteria: * Subject is a female of any race and ethnicity. * Subject is at least 25 years old * Subject has or will have a contrast enhanced breast MRI +/- 31 days of enrollment with no interval treatment or procedure between the two studies * Subject has BIRADS 6 or BIRADS 5 cancer or as determined by the radiologist * \>50% of the biopsied cancer mass must remain following biopsy OR * A calcification must be at least 2cm in maximum dimension prior to biopsy or at least 1cm in maximum dimension following biopsy Exclusion Criteria: * Subject is unable or unwilling to undergo informed consent * Subject has breast implant in the breast to be imaged * Subject is pregnant * Subject is breast feeding or lactating * Subject has a known allergy to gadolinium contrast agents. * Subject has a contraindication for MRI. * Subject suspected to be at risk to complication from the contrast agents. * Subject has a documented renal insufficiency, * Subject requires renal dialysis. * Subject has had a prior reaction to iodinated contrast. * Subject has had a prior episode of anaphylactic reaction to any substance. * Subject has taken metformin (Glucophage) within 48 hours of study procedures. * Subject has multiple allergies and/or severe asthma regularly treated with medication (prescription and/or over-the-counter).